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Pathways Recommended:	Cell Cycle/DNA Damage

Results for "

double-stranded DNA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA Methyltransferase (1) DNA Stain (3) DNA/RNA Synthesis (10) Antibiotic (1) Apoptosis (8) Bacterial (2) Bcl-2 Family (1) Biochemical Assay Reagents (3) Calcium Channel (1) Caspase (1) Checkpoint Kinase (Chk) (5) CMV (1) CRISPR/Cas9 (1) Endogenous Metabolite (6) Fluorescent Dye (2) G-quadruplex (1) Histone Methyltransferase (2) HSV (3) IFNAR (1) Isotope-Labeled Compounds (5) Na+/K+ ATPase (1) Orthopoxvirus (1) Parasite (3) Phosphodiesterase (PDE) (2) STING (4) Topoisomerase (1)
By Research Areas:	Cancer (17) Cardiovascular Disease (1) Infection (9) Inflammation/Immunology (8)

By Targets:

DNA Methyltransferase (1)

DNA Stain (3)

DNA/RNA Synthesis (10)

Antibiotic (1)

Apoptosis (8)

Bacterial (2)

Bcl-2 Family (1)

Biochemical Assay Reagents (3)

Calcium Channel (1)

Caspase (1)

Checkpoint Kinase (Chk) (5)

CMV (1)

CRISPR/Cas9 (1)

Endogenous Metabolite (6)

Fluorescent Dye (2)

G-quadruplex (1)

Histone Methyltransferase (2)

HSV (3)

IFNAR (1)

Isotope-Labeled Compounds (5)

Na+/K+ ATPase (1)

Orthopoxvirus (1)

Parasite (3)

Phosphodiesterase (PDE) (2)

STING (4)

Topoisomerase (1)

By Research Areas:

Cancer (17)

Cardiovascular Disease (1)

Infection (9)

Inflammation/Immunology (8)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: DNA-PK DNA Methyltransferase DNA Stain DNA Alkylator/Crosslinker DNA/RNA Synthesis

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-110137

Furamidine dihydrochloride 1 Publications Verification DB75 dihydrochloride; NSC 305831 dihydrochloride	Histone Methyltransferase Phosphodiesterase (PDE) Parasite	Infection Inflammation/Immunology Cancer
Furamidine dihydrochloride (DB75 dihydrochloride) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC₅₀ of 9.4 μM. Furamidine dihydrochloride is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC₅₀s of 166 µM, 283 µM, and >400 µM, respectively). Furamidine dihydrochloride is a potent, reversible and competitive *tyrosyl-DNA* phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1** by Furamidine dihydrochloride is effective both with single- and double-stranded DNA substrates but is slightly stronger with the duplex DNA. Furamidine dihydrochloride is also an antiparasite agent .

HY-18174

Prexasertib 15+ Cited Publications LY2606368	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity .

HY-119993

AR03 BMH-23	DNA/RNA Synthesis	Cancer
AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC₅₀ of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells .

HY-148411

Abetimus LJP 394 free base	Others	Inflammation/Immunology
Abetimus (LJP 394 free base) is an immunosuppressant consisting of four double-stranded DNA (dsDNA) oligonucleotides. Abetimus is capable of crosslinking anti-dsDNA antibodies on the surface of B cells, and decreases anti-dsDNA antibodies levels. Abetimus has the potential for research of systemic lupus erythematosus .

HY-110137A

Furamidine DB75; NSC 305831	Histone Methyltransferase Phosphodiesterase (PDE) Parasite	Infection Inflammation/Immunology Cancer
Furamidine (DB75) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC₅₀ of 9.4 μM. Furamidine is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC₅₀s of 166 µM, 283 µM, and >400 µM, respectively). Furamidine is a potent, reversible and competitive *tyrosyl-DNA* phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1** by Furamidine is effective both with single- and double-stranded DNA substrates but is slightly stronger with the duplex DNA. Furamidine is also an antiparasite agent .

HY-18174A

Prexasertib dihydrochloride 15+ Cited Publications LY2606368 dihydrochloride	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib dihydrochloride inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity .

HY-18174B

Prexasertib Mesylate Hydrate LY2606368 Mesylate Hydrate; LY2940930	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib Mesylate Hydrate inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib Mesylate Hydrate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib Mesylate Hydrate shows potent anti-tumor activity .

HY-18174C

Prexasertib mesylate LY2606368 mesylate	Checkpoint Kinase (Chk) DNA/RNA Synthesis Apoptosis	Cancer
Prexasertib mesylate (LY2606368 mesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib mesylate inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib mesylate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib mesylate shows potent anti-tumor activity .

HY-18174E

Prexasertib dimesylate 15+ Cited Publications LY2606368 dimesylate	Checkpoint Kinase (Chk) Apoptosis	Cancer
Prexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K_i of 0.9 nM and an IC₅₀ of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC₅₀=8 nM) and RSK1 (IC₅₀=9 nM). Prexasertib dimesylate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti-tumor activity .

HY-W040329

2'-Deoxyadenosine

Endogenous Metabolite Others

2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

2'-Deoxyadenosine	Endogenous Metabolite	Others
2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-135009

2-Di-1-ASP DASPI	G-quadruplex	Others
2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .

HY-109517

Calf thymus DNA DNA from calf thymus, Thymonucleic acid	DNA/RNA Synthesis	Inflammation/Immunology Cancer
Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents .

HY-160226

ISD Control sodium	STING	Inflammation/Immunology
ISD (interferon stimulatory DNA) Control sodium is a non-immunostimulatory single-stranded oligonucleotide with the same sequence as ISD, its double-stranded counterpart .

HY-D0814

DAPI dihydrochloride 35+ Cited Publications 4',6-Diamidino-2-phenylindole dihydrochloride	DNA Stain	Others
DAPI dihydrochloride is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells .

HY-111183

Neocarzinostatin Zinostatin; Vinostatin	DNA/RNA Synthesis Bacterial Apoptosis Antibiotic	Infection Cancer
Neocarzinostatin, a potent *DNA-damaging, anti-tumor antibiotic, recognizes double-stranded* DNA bulge and induces DNA double strand breaks (DSBs). Neocarzinostatin induces apoptosis. Neocarzinostatin has potential for EpCAM-positive cancers treatment .

HY-E70220

AsCas12a Nuclease

CRISPR/Cas9 Others

AsCas12a Nuclease is a CRISPR nuclease, and can specifically cutting double-stranded DNA. AsCas12a Nuclease can be used for gene edited study .

AsCas12a Nuclease	CRISPR/Cas9	Others
AsCas12a Nuclease is a CRISPR nuclease, and can specifically cutting double-stranded DNA. AsCas12a Nuclease can be used for gene edited study .

HY-P2773

Nuclease S1, Aspergillus oryzae	DNA/RNA Synthesis	Others
Nuclease S1, Aspergillus oryzae is a specific endonuclease that degrades single stranded DNA (ssDNA) and RNA. Nuclease S1 can also remove protruding single-strand ends from double-stranded DNA .

HY-D1396

Br-DAPI 3 Publications Verification	Fluorescent Dye DNA Stain	Others
Br-DAPI is a marker dye in DAPI series. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells . Storage: Keep away from light.

HY-E70094

T4 UvsX Recombinase	DNA/RNA Synthesis	Others
T4 UvsX Recombinase helps initiate DNA replication on a double-stranded DNA template by catalyzing synapsis between the template and a homologous DNA single strand that serves as primer. T4 UvsX Recombinase greatly amplifies the snap-back (hairpin-primed) DNA synthesis that is catalyzed by the T4 DNA polymerase holoenzyme on linear, single-stranded DNA templates .

HY-153118

Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers ctDNA sodium, Type I, fibers; DNA sodium, from calf thymus, Type I, fibers; Thymonucleic acid sodium, Type I, fibers	Biochemical Assay Reagents	Others Cancer
Deoxyribonucleic acid sodium, from calf thymus, Type I, fibers is the sodium salts form of Calf thymus DNA (HY-109517). Calf thymus DNA is a double-stranded template DNA isolated from calf thymus. It can be used to study the interaction between DNA and DNA binding agents, as well as the structure and function of DNA, for DNA quantification and used as a substrate for DNA polymerase analysis, etc .

HY-119182

Mitonafide NSC 300288	DNA/RNA Synthesis	Cancer
Mitonafide (NSC 300288) is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia .

HY-160223

ssVACV-70mer sodium	STING	Infection Inflammation/Immunology
ssVACV-70mer sodium is a 70 bp single-stranded oligonucleotide containing viral DNA motifs that derive from the vaccinia virus DNA. Unlike its double-stranded counterpart dsVACV 70mer, ssVACV 70mer is not IFN-inducer .

HY-160224

dsVACV-70mer sodium	STING IFNAR	Inflammation/Immunology
dsVACV-70mer (sodium) is a 70 bp double-stranded oligonucleotide containing viral DNA motifs derived from vaccinia virus DNA. dsVACV-70mer (sodium) has potently induces IFN-β via a STING-dependent manner .

HY-W040329S2

2'-Deoxyadenosine-d13	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxyadenosine-d₁₃ is deuterium labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-W040329S1

2'-Deoxyadenosine-13C10	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxyadenosine- ¹³C₁₀ is ¹³C-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-149900

Antiviral agent 33	Biochemical Assay Reagents	Infection
Antiviral agent 33 (compound 1c) is a double-stranded DNA (dsDNA) virus inhibitor with IC₅₀ values of 0.0790 and 0.1572 µM for VACV and AdV5, respectively. Antiviral agent 33 also has potential for oral administration .

HY-400705

Duocarmycin SA intermediate-1	Others	Cancer
Duocarmycin SA intermediate-1 is an intermediate in the synthesis of the antibiotic Duocarmycin SA (HY-12456). Duocarmycin SA intermediate-1 induces sequence-selective alkylation of double-stranded DNA and has synergistic, tumor-suppressive cytotoxicity with proton irradiation .

HY-400706

Duocarmycin SA intermediate-2	Others	Cancer
Duocarmycin SA intermediate-2 is an intermediate in the synthesis of the antibiotic Duocarmycin SA (HY-12456). Duocarmycin SA intermediate-2 induces sequence-selective alkylation of double-stranded DNA and has synergistic, tumor suppressor cytotoxicity with proton irradiation .

HY-155693

Topoisomerase II inhibitor 16	Topoisomerase Parasite	Infection
Topoisomerase II inhibitor 16 (compound CT3) is a selective, orally active, brain-penetrant and irreversible trypanosomal topoisomerase II inhibitor by stabilizing double-stranded DNA:enzyme cleavage complexes. Topoisomerase II inhibitor 16 has the potential for Chagas disease research .

HY-W040329S

2'-Deoxyadenosine-13C10,15N5	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxyadenosine- ¹³C₁₀, ¹⁵N₅ is ¹³C and ¹⁵N-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-W040329S3

2'-Deoxyadenosine-15N5,d13	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxyadenosine- ¹⁵N₅,d₁₃ is deuterium and ¹⁵N labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-W751961

2'-Deoxyadenosine-15N5	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxyadenosine-15N5 is the ¹⁵N₅-labeled version of 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative that can pair with deoxythymidine in double-stranded DNA.

HY-158116

VVD-214 RO7589831; VVD-133214	DNA/RNA Synthesis	Cancer
VVD-214 is a synthetic lethal allosteric inhibitor of WRN helicase. VVD-214 covalently binds to cysteine 727 of WRN and inhibits ATP hydrolysis and helicase activity. VVD-214 is potent in causing double-stranded DNA breaks, nuclear swelling, and cell death in high microsatellite instability (MSI) cancers.

HY-16401

Zalypsis PM00104	Apoptosis	Cancer
Zalypsis (PM00104) has anti-tumor activity. Zalypsis binds to DNA and shows cytotoxicity. Zalypsis inhibits cell cycle and transcription, and leads to double stranded DNA breaks .

HY-D0815

Propidium Iodide Maximum Cited Publications 38 Publications Verification	Fluorescent Dye DNA/RNA Synthesis	Others
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.

HY-E70090

T7 RNA polymerase	DNA/RNA Synthesis	Others
T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg ²⁺, T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter .

HY-B1357

Digitoxin 3 Publications Verification	Bcl-2 Family Caspase Apoptosis HSV Na+/K+ ATPase Calcium Channel	Cardiovascular Disease Cancer
Digitoxin is an anti-cancer agent. Digitoxin induces apoptosis, inhibits influenza cytokine storm, causes DNA double-stranded breaks (DSBs) and blocks the cell cycle at the G2/M phase. Digitoxin induces calcium uptake into cells by forming transmembrane calcium channels and can be used for research of heart failure .

HY-E70206

CpG Methyltransferase CpG	DNA Methyltransferase Biochemical Assay Reagents	Others
CpG Methyltransferase is a DNA methyltransferase. CpG Methyltransferase can methylate the C5 position on the base moiety of all cytosine nucleotides contained in unmethylated or hemimethylated double stranded DNA in a 5’-CpG-3’ context .

HY-14532

Brincidofovir 2 Publications Verification CMX001; HDP-CDV	CMV HSV Orthopoxvirus	Infection
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir (HY-17438), is an orally available, long-acting antiviral. Brincidofovir shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections. Brincidofovir, an oral antiviral in late stage development, has proven effective against orthopoxviruses in vitro and in vivo. .

HY-160222

HSV-60mer sodium	HSV STING	Infection Inflammation/Immunology
HSV-60mer sodium is a 60 bp double-stranded oligonucleotide containing viral DNA motifs that derive from the herpes simplex virus 1 (HSV-1) genome . Transfected HSV-60 has been shown to potently induce IFN-β in a Toll-like receptor (TLR)-, DNA-dependent activator of IRFs (DAI)-, and RNA polymerase III (Pol III)-independent, but STING-, TBK1- and IFN regulatory factor 3 (IRF3)-dependent manner.

HY-D0971

Pyronin Y 3 Publications Verification Pyronine G; C.I. 45005	DNA Stain	Others
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells .

HY-P5740

Cacaoidin	Bacterial	Infection
Cacaoidin is a glycosylated lantibiotic isolated from a Streptomyces cacaoi strain. Cacaoidin has potent antibacterial activity against Gram-positive pathogens including Clostridium difficile .

Cat. No.	Product Name	Type

HY-135009

2-Di-1-ASP DASPI	Fluorescent Dyes/Probes
2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .

HY-D0814

DAPI dihydrochloride 35+ Cited Publications 4',6-Diamidino-2-phenylindole dihydrochloride	Fluorescent Dyes/Probes
DAPI dihydrochloride is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells .

DAPI dihydrochloride

35+ Cited Publications

4',6-Diamidino-2-phenylindole dihydrochloride

Fluorescent Dyes/Probes

DAPI dihydrochloride is a DAPI dye. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. In addition, because DAPI can pass through intact cell membranes, it can be used to stain both live and fixed cells .

HY-D0815

Propidium Iodide Maximum Cited Publications 38 Publications Verification	Fluorescent Dyes/Probes
Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.

Propidium Iodide

Maximum Cited Publications

38 Publications Verification

Fluorescent Dyes/Probes

Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.

HY-D0971

Pyronin Y 3 Publications Verification Pyronine G; C.I. 45005	Fluorescent Dyes/Probes
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W040329

2'-Deoxyadenosine	Natural Products Immune System Disorder Classification of Application Fields Source classification Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-B1357

Digitoxin 3 Publications Verification	Cardiovascular Disease Digitalis purpurea Linn. Structural Classification Microorganisms Classification of Application Fields Source classification Scrophulariaceae Plants Disease Research Fields Steroids	Bcl-2 Family Caspase Apoptosis HSV Na+/K+ ATPase Calcium Channel
Digitoxin is an anti-cancer agent. Digitoxin induces apoptosis, inhibits influenza cytokine storm, causes DNA double-stranded breaks (DSBs) and blocks the cell cycle at the G2/M phase. Digitoxin induces calcium uptake into cells by forming transmembrane calcium channels and can be used for research of heart failure .

HY-109517

Calf thymus DNA DNA from calf thymus, Thymonucleic acid	Natural Products Animals Source classification Inflammation/Immunology Disease Research Fields Cancer	DNA/RNA Synthesis
Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents .

Cat. No.	Product Name	Chemical Structure

HY-W040329S2

2'-Deoxyadenosine-d13
2'-Deoxyadenosine-d₁₃ is deuterium labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-W040329S1

2'-Deoxyadenosine-13C10
2'-Deoxyadenosine- ¹³C₁₀ is ¹³C-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-W040329S

2'-Deoxyadenosine-13C10,15N5
2'-Deoxyadenosine- ¹³C₁₀, ¹⁵N₅ is ¹³C and ¹⁵N-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-W040329S3

2'-Deoxyadenosine-15N5,d13
2'-Deoxyadenosine- ¹⁵N₅,d₁₃ is deuterium and ¹⁵N labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.

HY-W751961

2'-Deoxyadenosine-15N5
2'-Deoxyadenosine-15N5 is the ¹⁵N₅-labeled version of 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative that can pair with deoxythymidine in double-stranded DNA.

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double-stranded DNA

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